Wednesday, June 25, 2014
Friday, June 20, 2014
hilo de plastico de botellas
http://www.trueactivist.com/this-guy-found-a-clever-way-to-reuse-plastic-bottles/
Sunday, May 25, 2014
artemesia annua l.,huaya,chaya
hello m . everything fine ?From the point off view off herbal medicine i
recapitulate¨, the wormwood extract from artemisia annua l was
originally used as an infusion for the treatment off malaria , after the
archeologicial recovery off the recipe in china it became used and
produced in africa and asia from the seventies on,. alcoholic solutions
-tincture- give a higher compound concentration, the tablets used on the
base off the dry extract in some cases suggests allergic deadly
reactions in tanzania one text mentioned-as a cancer treatment for
breastcancer it can be very effective with the extracted component
artemisinin in watery solution and pumping up the iron content off
cancer cells at the same time with holotransferrin, in herbal medicin
context , there has to be looked to natural ways to enhance the iron
content off cancer cells , which naturally is higher than healthy cells,
and so the artemisinin does its work very efficient, that artemisinin
part could be done with the infusion or an alcoholic tincture from the
point off view off natural medicin, for the pumping up off the iron
content off cancer cells a remedy can posibly be found....it just needs
some more random literature research at its best, the dried extract is
very high in concentration so the tincture or the infusion could sail
around most alergic reactions i guess....so far so good...wish you all
the best
,wormwood originally used to combat malaria, the recipe was undigged in an archeological dig in the 70ties
This is an archived article.
November 26, 2001
Ancient Chinese folk remedy may hold key to non-toxic cancer treatment
Rob Harrill
Posted under: Archive
Two bioengineering researchers at the University of Washington have discovered a promising potential treatment for cancer among the ancient arts of Chinese folk medicine.
Research Professor Henry Lai and assistant research Professor Narendra Singh have exploited the chemical properties of a wormwood derivative to target breast cancer cells, with surprisingly effective results. A study in the latest issue of the journal Life Sciences describes how the derivative killed virtually all human breast cancer cells exposed to it within 16 hours.
“Not only does it appear to be effective, but it’s very selective,” Lai said. “It’s highly toxic to the cancer cells, but has a marginal impact on normal breast cells.”
The compound, artemisinin, isn’t new. It apparently was extracted from the plant Artemesia annua L., commonly known as wormwood, thousands of years ago by the Chinese, who used it to combat malaria. However, the treatment was lost over time. Artemisinin was rediscovered during an archaeological dig in the 1970s that unearthed recipes for ancient medical remedies, and has become widely used in modern Asia and Africa to fight the mosquito-borne disease.
The compound helps control malaria because it reacts with the high iron concentrations found in the malaria parasite. When artemisinin comes into contact with iron, a chemical reaction ensues, spawning charged atoms that chemists call “free radicals.” The free radicals attack cell membranes, breaking them apart and killing the single-cell parasite.
About seven years ago, Lai began to hypothesize that the process might work with cancer, too.
“Cancer cells need a lot of iron to replicate DNA when they divide,” Lai explained. “As a result, cancer cells have much higher iron concentrations than normal cells. When we began to understand how artemisinin worked, I started wondering if we could use that knowledge to target cancer cells.”
Lai devised a potential method and began to look for funding, obtaining a grant from the Breast Cancer Fund in San Francisco. Meanwhile, the UW patented his idea.
The thrust of the idea, according to Lai and Singh, was to pump up the cancer cells with maximum iron concentrations, then introduce artemisinin to selectively kill the cancer. To accommodate a rate of iron intake greater than normal cells, cancer cell surfaces feature greater concentrations of transferrin receptors — cellular pathways that allow iron into a cell. Breast cancer cells are no exception. They have five to 15 times more transferrin receptors on their surface than normal breast cells.
In the current study, the researchers subjected sets of breast cancer cells and normal breast cells to doses of holotransferrin (which binds with transferrin receptors to transport iron into cells), dihydroartemisinin (a more water-soluble form of artemisinin) and a combination of both compounds. Cells exposed to just one of the compounds showed no appreciable effect. Normal breast cells, exposed to both compounds, exhibited a minimal effect. But the response by cancer cells when hit with first holotransferrin, then dihydroartemisinin, was dramatic.
After eight hours, just 25 percent of the cancer cells remained. By the time 16 hours had passed, nearly all the cells were dead.
An earlier study involving leukemia cells yielded even more impressive results. Those cells were eliminated within eight hours. A possible explanation might be the level of iron in the leukemia cells.
“They have one of the highest iron concentrations among cancer cells,” Lai explained. “Leukemia cells can have more than 1,000 times the concentration of iron that normal cells have.”
The next step, according to Lai, is animal testing. Limited tests have been done in that area. In an earlier study, a dog with bone cancer so severe it couldn’t walk made a complete recovery in five days after receiving the treatment. But more rigorous testing is needed.
If the process lives up to its early promise, it could revolutionize the way some cancers are approached, Lai said. The goal would be a treatment that could be taken orally, on an outpatient basis.
“That would be very easy, and this could make that possible,” Lai said. “The cost is another plus — at $2 a dose, it’s very cheap. And, with the millions of people who have already taken artemisinin for malaria, we have a track record showing that it’s safe.”
Whatever happens, Lai said, a portion of the credit will have to go to unknown medical practitioners, long gone now.
“The fascinating thing is that this was something the Chinese used thousands of years ago,” he said. “We simply found a different application.”
###
For more information, contact Lai at (206) 543-1071 or http://www.elsevier.com/locate/lifescie
Share this:
FacebookTwitterEmailPrint
Related StoriesAncient Chinese remedy shows potential in preventing breast cancer December 19, 2005
UW licenses potential cancer treatment derived from ancient Chinese folk remedy October 14, 2004
An ancient remedy reborn: UW licenses potential wormwood treatment for cancer
Ancient Chinese remedy proves effective against cancer cells November 29, 2001
http://www.washington.edu/news/2001/11/26/ancient-chinese-folk-remedy-may-hold-key-to-non-toxic-cancer-treatment/
,wormwood originally used to combat malaria, the recipe was undigged in an archeological dig in the 70ties
This is an archived article.
November 26, 2001
Ancient Chinese folk remedy may hold key to non-toxic cancer treatment
Rob Harrill
Posted under: Archive
Two bioengineering researchers at the University of Washington have discovered a promising potential treatment for cancer among the ancient arts of Chinese folk medicine.
Research Professor Henry Lai and assistant research Professor Narendra Singh have exploited the chemical properties of a wormwood derivative to target breast cancer cells, with surprisingly effective results. A study in the latest issue of the journal Life Sciences describes how the derivative killed virtually all human breast cancer cells exposed to it within 16 hours.
“Not only does it appear to be effective, but it’s very selective,” Lai said. “It’s highly toxic to the cancer cells, but has a marginal impact on normal breast cells.”
The compound, artemisinin, isn’t new. It apparently was extracted from the plant Artemesia annua L., commonly known as wormwood, thousands of years ago by the Chinese, who used it to combat malaria. However, the treatment was lost over time. Artemisinin was rediscovered during an archaeological dig in the 1970s that unearthed recipes for ancient medical remedies, and has become widely used in modern Asia and Africa to fight the mosquito-borne disease.
The compound helps control malaria because it reacts with the high iron concentrations found in the malaria parasite. When artemisinin comes into contact with iron, a chemical reaction ensues, spawning charged atoms that chemists call “free radicals.” The free radicals attack cell membranes, breaking them apart and killing the single-cell parasite.
About seven years ago, Lai began to hypothesize that the process might work with cancer, too.
“Cancer cells need a lot of iron to replicate DNA when they divide,” Lai explained. “As a result, cancer cells have much higher iron concentrations than normal cells. When we began to understand how artemisinin worked, I started wondering if we could use that knowledge to target cancer cells.”
Lai devised a potential method and began to look for funding, obtaining a grant from the Breast Cancer Fund in San Francisco. Meanwhile, the UW patented his idea.
The thrust of the idea, according to Lai and Singh, was to pump up the cancer cells with maximum iron concentrations, then introduce artemisinin to selectively kill the cancer. To accommodate a rate of iron intake greater than normal cells, cancer cell surfaces feature greater concentrations of transferrin receptors — cellular pathways that allow iron into a cell. Breast cancer cells are no exception. They have five to 15 times more transferrin receptors on their surface than normal breast cells.
In the current study, the researchers subjected sets of breast cancer cells and normal breast cells to doses of holotransferrin (which binds with transferrin receptors to transport iron into cells), dihydroartemisinin (a more water-soluble form of artemisinin) and a combination of both compounds. Cells exposed to just one of the compounds showed no appreciable effect. Normal breast cells, exposed to both compounds, exhibited a minimal effect. But the response by cancer cells when hit with first holotransferrin, then dihydroartemisinin, was dramatic.
After eight hours, just 25 percent of the cancer cells remained. By the time 16 hours had passed, nearly all the cells were dead.
An earlier study involving leukemia cells yielded even more impressive results. Those cells were eliminated within eight hours. A possible explanation might be the level of iron in the leukemia cells.
“They have one of the highest iron concentrations among cancer cells,” Lai explained. “Leukemia cells can have more than 1,000 times the concentration of iron that normal cells have.”
The next step, according to Lai, is animal testing. Limited tests have been done in that area. In an earlier study, a dog with bone cancer so severe it couldn’t walk made a complete recovery in five days after receiving the treatment. But more rigorous testing is needed.
If the process lives up to its early promise, it could revolutionize the way some cancers are approached, Lai said. The goal would be a treatment that could be taken orally, on an outpatient basis.
“That would be very easy, and this could make that possible,” Lai said. “The cost is another plus — at $2 a dose, it’s very cheap. And, with the millions of people who have already taken artemisinin for malaria, we have a track record showing that it’s safe.”
Whatever happens, Lai said, a portion of the credit will have to go to unknown medical practitioners, long gone now.
“The fascinating thing is that this was something the Chinese used thousands of years ago,” he said. “We simply found a different application.”
###
For more information, contact Lai at (206) 543-1071 or http://www.elsevier.com/locate/lifescie
Share this:
FacebookTwitterEmailPrint
Related StoriesAncient Chinese remedy shows potential in preventing breast cancer December 19, 2005
UW licenses potential cancer treatment derived from ancient Chinese folk remedy October 14, 2004
An ancient remedy reborn: UW licenses potential wormwood treatment for cancer
Ancient Chinese remedy proves effective against cancer cells November 29, 2001
http://www.washington.edu/news/2001/11/26/ancient-chinese-folk-remedy-may-hold-key-to-non-toxic-cancer-treatment/
- chaya, that grows here, is also supposed to be good
Saturday, May 24, 2014
planta para tratamiento de cancer-cancertreatment
This Little Known Chinese Herb Kills 12,000 Cancer Cells For Every Healthy Cell
March 26, 2014 by Arjun Walia. 26 Comments.
Share on Facebook Twitter
Seleccionar idioma▼Today, odds are that you have had/have cancer, or know somebody who does. In Canada, approximately one million Canadians that were alive at the beginning of 2009 have had a cancer diagnosis in the previous 10 years. Two out of every five Canadians will develop cancer within their life time, and one in every four will die.(3) In the United States, one out of every two men, and one out of ever three women will become infected with cancer.
These rates have continued to skyrocket since we started recording them and more people are starting to ask questions and observe the environment we choose to surround ourselves with on a daily basis.
Despite these statistics, new research is emerging everyday that puts into question the only two approved treatments for cancer, which are radiation and chemotherapy. It seems we are approaching a time where the medical community will be forced to open up to new options when it comes to cancer treatment. After all, scientists have discovered that chemotherapy fuels cancer growth and kills the patient more quickly, yet nothing has been changed, both are extremely toxic to the human body.
A little known Chinese herb might be eligible for the growing list of cancer killers via alternative methods of treatment. According to studies published in Life Sciences, Cancer Letters and Anticancer Drugs, artemesinin, a derivative of the wormwood plant commonly used in Chinese medicine, can kill off cancer cells, and do it at a rate of 12,000 cancer cells for every healthy cell. (0)
Henry Lai and his team of researchers from the University of Washington synthesized the compound, which uses a cancer cells appetite for iron to make them the target. The great thing about artemisinin is that alone it can selectively kill cancer cells while leaving normal cells unharmed.
“By itself, artemisinin is about 100 times more selective in killing cancer cells as opposed to normal cells. Artemisinin is 34,000 times more potent in killing the cancer cells as opposed to their normal cousins. So the tagging process appears to have greatly increased the potency of artemisinin’s cancer-killing properties.” - Henry Lai
Despite the compound being licensed to Holley Pharmaceuticals, it has yet to be used for cancer treatment in humans.
“We call it a Trojan horse because the cancer cell recognizes transferrin as a natural, harmless protein. So the cell picks up the compound without knowing that a bomb (artemisinin) is hidden inside.” - Henry Lai
The wormwood extract was used many centuries ago in China for healing purposes. The treatment became lost over time and has now been rediscovered thanks to an ancient manuscript containing medical remedies. It kills 12,000 cancer cells for every healthy cell, which means it could be turned into a drug with minimal side effects.
“The compound is currently being licensed by the University of Washington to Artemisia Biomedical Inc., a company that Lai, Sasaki and Narendra Singh, UW associate professor of bioengineering, founded in Newcastle, Washington for development and commercialization. Human trials are at least several years away. Artemisinin is readily available, Sasaki said, and he hopes their compound can eventually be cheaply manufactured to help cancer patients in developing countries.” (0)
The abstracts read:
“Artemisinin reacts with iron to form free radicals that kill cells. Since cancer cells uptake relatively larger amounts of iron than normal cells, they are more susceptible to the toxic effect of artemisinin. In previous research, we have shown that artemisinin is more drawn to cancer cells than to normal cells. In the present research, we covalently attached artemisinin to the iron-carying plasma glycoprotein transferrin.Transferrin is transported into the cells via receptor-mediated endocytosis and cancer cells express significantly more transferrin receptors on their cell surface and endocytose more transferrin than normal cells. Thus, we hypothesize that by tagging artemisinin to transferrin, both iron and artemisinin would be transported into cancer cells in one package. Once inside a cell, iron is released and can readily react with artemisinin close by tagged to the transferrin. This would enhance the toxicity and selectivity of artemisinin towards cancer cells. We found that holotransferrin-tagged artemisinin, when compared with artemisinin, was very potent and selective in killing cancer cells. Thus, this ‘tagged-compound’ could potentially be developed into an effective chemotherapeutic agent for cancer treatment.” (1)
Another abstract reads:
“Our results demonstrate that the artemisinin disruption of E2F1 transcription factor expression mediates the cell cycle arrest of human breast cancer cells and represents a critical transcriptional pathway by which artemisinin controls human reproductive cancer cell growth.” (2)
Artemisinin is currently FDA approved for the treatment of malaria, it’s very safe and easy to use. It’s inexpensive and works on all cancers but has yet to find it’s way into the mainstream. It’s really time to move beyond just radiation, surgery and chemotherapy for the treatment of cancer.
March 26, 2014 by Arjun Walia. 26 Comments.
Share on Facebook Twitter
Seleccionar idioma▼Today, odds are that you have had/have cancer, or know somebody who does. In Canada, approximately one million Canadians that were alive at the beginning of 2009 have had a cancer diagnosis in the previous 10 years. Two out of every five Canadians will develop cancer within their life time, and one in every four will die.(3) In the United States, one out of every two men, and one out of ever three women will become infected with cancer.
These rates have continued to skyrocket since we started recording them and more people are starting to ask questions and observe the environment we choose to surround ourselves with on a daily basis.
Despite these statistics, new research is emerging everyday that puts into question the only two approved treatments for cancer, which are radiation and chemotherapy. It seems we are approaching a time where the medical community will be forced to open up to new options when it comes to cancer treatment. After all, scientists have discovered that chemotherapy fuels cancer growth and kills the patient more quickly, yet nothing has been changed, both are extremely toxic to the human body.
A little known Chinese herb might be eligible for the growing list of cancer killers via alternative methods of treatment. According to studies published in Life Sciences, Cancer Letters and Anticancer Drugs, artemesinin, a derivative of the wormwood plant commonly used in Chinese medicine, can kill off cancer cells, and do it at a rate of 12,000 cancer cells for every healthy cell. (0)
Henry Lai and his team of researchers from the University of Washington synthesized the compound, which uses a cancer cells appetite for iron to make them the target. The great thing about artemisinin is that alone it can selectively kill cancer cells while leaving normal cells unharmed.
“By itself, artemisinin is about 100 times more selective in killing cancer cells as opposed to normal cells. Artemisinin is 34,000 times more potent in killing the cancer cells as opposed to their normal cousins. So the tagging process appears to have greatly increased the potency of artemisinin’s cancer-killing properties.” - Henry Lai
Despite the compound being licensed to Holley Pharmaceuticals, it has yet to be used for cancer treatment in humans.
“We call it a Trojan horse because the cancer cell recognizes transferrin as a natural, harmless protein. So the cell picks up the compound without knowing that a bomb (artemisinin) is hidden inside.” - Henry Lai
The wormwood extract was used many centuries ago in China for healing purposes. The treatment became lost over time and has now been rediscovered thanks to an ancient manuscript containing medical remedies. It kills 12,000 cancer cells for every healthy cell, which means it could be turned into a drug with minimal side effects.
“The compound is currently being licensed by the University of Washington to Artemisia Biomedical Inc., a company that Lai, Sasaki and Narendra Singh, UW associate professor of bioengineering, founded in Newcastle, Washington for development and commercialization. Human trials are at least several years away. Artemisinin is readily available, Sasaki said, and he hopes their compound can eventually be cheaply manufactured to help cancer patients in developing countries.” (0)
The abstracts read:
“Artemisinin reacts with iron to form free radicals that kill cells. Since cancer cells uptake relatively larger amounts of iron than normal cells, they are more susceptible to the toxic effect of artemisinin. In previous research, we have shown that artemisinin is more drawn to cancer cells than to normal cells. In the present research, we covalently attached artemisinin to the iron-carying plasma glycoprotein transferrin.Transferrin is transported into the cells via receptor-mediated endocytosis and cancer cells express significantly more transferrin receptors on their cell surface and endocytose more transferrin than normal cells. Thus, we hypothesize that by tagging artemisinin to transferrin, both iron and artemisinin would be transported into cancer cells in one package. Once inside a cell, iron is released and can readily react with artemisinin close by tagged to the transferrin. This would enhance the toxicity and selectivity of artemisinin towards cancer cells. We found that holotransferrin-tagged artemisinin, when compared with artemisinin, was very potent and selective in killing cancer cells. Thus, this ‘tagged-compound’ could potentially be developed into an effective chemotherapeutic agent for cancer treatment.” (1)
Another abstract reads:
“Our results demonstrate that the artemisinin disruption of E2F1 transcription factor expression mediates the cell cycle arrest of human breast cancer cells and represents a critical transcriptional pathway by which artemisinin controls human reproductive cancer cell growth.” (2)
Artemisinin is currently FDA approved for the treatment of malaria, it’s very safe and easy to use. It’s inexpensive and works on all cancers but has yet to find it’s way into the mainstream. It’s really time to move beyond just radiation, surgery and chemotherapy for the treatment of cancer.
Monday, April 07, 2014
Saturday, April 05, 2014
Sunday, March 30, 2014
Saturday, March 29, 2014
Monday, March 24, 2014
botellas de plastico reciclando en cajas
A dica de hoje é extremamente interessante.
Vamos mostrar como fazer uma caixinha com garrafas pet. Além de ter um
objeto exclusivo e muito útil, você ajuda a evitar que garrafas pet vão
parar em rios, nas ruas, entupindo bueiros e causando problemas.
1)
Você vai precisar de tesoura, alicate, fita crepe, quatro garrafas PET
cortadas em tiras de 2cm de largura, elásticos e um molde de 10x10x10cm
2) Corte uma tira em um comprimento que
permita cobrir dois lados mais o fundo da caixa, deixando ainda 4cm de
sobra em cada ponta
3) Ajuste a fita ao molde, cobrindo dois lados e o fundo. Vinque as sobras de 4cm para facilitar o trabalho
4) Passe elásticos em torno do molde a fim de fixar melhor as fitas
5) Corte mais quatro fitas e ajuste-as ao molde como explicado nos passos 2 e 3
6) Corte mais cinco fitas para cobrir os dois outros lados do molde
7) Quando for passar a primeira fita dessa
segunda etapa, será necessário entrelaçá-la, na parte de baixo, com as
fitas que já estão fixas. Para isso, basta realizar tecelagem simples,
passando a fita ora por baixo, ora por cima das fitas já dispostas
8) Faça o mesmo com as demais fitas da
segunda etapa. Lembre-se de que, ao fazer o entrelaçamento, onde a fita
anterior passou por baixo da trama, a fita atual deve passar por cima e
vice-versa. A etapa seguinte será fazer as laterais da caixa. Para isso,
corte cinco fitas em comprimento suficiente para cobrir quatro lados e
deixar uma sobra de cerca de 10cm.
9) Quando for entrelaçar a primeira fita,
cuide para que ela fique desencontrada com a fita paralela a ela no
fundo da caixa. Isto é, onde a fita do fundo passa por baixo da trama, a
fita da lateral deve passar por cima e vice-versa. Começe tecendo da
direita para a esquerda, parando a ponta da fita na última posição em
que ela fique por cima da trama. Segure a fita nessa posição, pegue a
outra extremidade e começe a tecer da esquerda para a direita, avançando
para o lado seguinte.
10) Entrelaçe a fita em volta de toda a caixa
11) Quando chegar a hora de arrematar,
sobreponha a sobra de fita ao trecho já tramado. A extremidade da fita
deve ficar por baixo da trama
12) Repita, com outras três fitas, o procedimento descrito nos passos de 9 a 11. Não utilize, por enquanto, a quinta fita
13) Pegue a fita restante e corte-a no meio no sentido do comprimento
14) Passe as fitas finas pela trama normalmente, seguindo o mesmo procedimento utilizado para as demais
15) Agora é ncessário arrematar as sobras
na parte de cima da caixa. Para as fitas verticais que estiverem por
baixo das horizontais, dobre a sobra para fora, rente à borda da caixa
16) Corte as sobras na altura da terceira
fita de cima para baixo. Arremate as pontas encaixando-as nas terceira
fita. Dobre as demais sobras para fora e corte-as na altura da terceira
fita. Retire a caixa do molde e arremate estas últimas sobras para
dentro, encaixando-as na terceira fita
17) Reforçe os vincos. Utilize o alicate para vincar bem as bordas (protegendo a peça com um pedaço de fita de PET dobrada)
18) Pronto! A caixa de fitas de PET que
você acabou de confeccionar é ideal para guardar miudezas ou mesmo
embalar presentes. Utilizando a técnica mostrada aqui, você pode montar
caixas no tamanho que quiser.
Fontes:
Tuesday, February 25, 2014
biotectura y calientador de garrafas pet
Saturday, February 01, 2014
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